2018; 38(1): 37, © 2008 Indian Journal of Pathology and Microbiology | Published by Wolters Kluwer -. It is a rare disease of unknown aetiology and can be life-threatening. The disorders are name after a British physician who first described systemic juvenile rheumatoid arthritis in the medical literature in 1896. Myocarditis. Introduction. Keywords: Arthritis, Myocarditis, Idiopathic, Interleukin, Juvenile. Numerous bacteria can cause myocarditis, including staphylococcus, streptococcus, the bacterium that causes diphtheria and the tick-borne bacterium responsible for Lyme disease. Myocarditis in association with cardiac dysfunction is classified as inflammatory cardiomyopathy usually caused by infection, autoimmune diseases, or responses to toxic substances. Meijvis SC, Endeman H, Geers AB, ter Borg EJ. It's characterized by sudden, severe attacks of pain, swelling, redness and tenderness in the joints, often the joint at the base of the big toe.An attack of gout can occur suddenly, often waking you up in the middle of the night with the sensation that your big toe is on fire. Kristensen LE, Bartosik I. Myocarditis in adult-onset Still's disease despite significant immunosuppressive therapy. RA patients are at increased risk for developing heart failure and inflammatory myocarditis potentially contributes to this excess risk. If you do not receive an email within 10 minutes, your email address may not be registered, The initial phase of myocarditis is associated with the presence of infectious virus and is characterized by focal necrosis and infiltrates of polymorphonuclear and mononuclear inflammatory cells. Myocarditis describes a heterogeneous group of disorders characterized by myocardial inflammation in the absence of predominant acute or chronic ischemia. It is a rare disease of unknown aetiology and can have serious systemic and musculoskeletal sequelae. Myocarditis can affect your heart muscle and your heart's electrical system, reducing your heart's ability to pump and causing rapid or abnormal heart rhythms (arrhythmias).A viral infection usually causes myocarditis, but it can result from a reaction to a drug or be part of a more general inflammatory condition. 1 Department of Pathology and Laboratory Science, Armed Forces Medical College, Command Hospital, Pune, Maharashtra, India2 Department of Internal Medicine, Armed Forces Medical College, Command Hospital, Pune, Maharashtra, India This case illustrates myocarditis as a fatal complication of soJIA, potentially enabled by anakinra. Autoantibodies are frequently present, some are … Reginato AJ, Schumacher HR Jr, Baker DG, O'Connor CR, Ferreiros J. Systemic onset juvenile idiopathic arthritis (soJIA) is a chronic auto-inflammatory disease of childhood characterized by quotidian fever, evanescent rash, serositis, lymphadenopathy, splenomegaly, and synovial joint … Rheumatoid arthritis is a chronic inflammatory disorder that typically affects the joints and other body parts, such as the skin, eyes, lungs, heart and blood vessels.. RA is an autoimmune disorder, a condition where the body’s immune system attacks its own tissues.. Osteoarthritis occurs as a result of wear and tear of the joints. Gout is a common and complex form of arthritis that can affect anyone. In these diseases, called autoimmune disorders, the body's normally protective immune system causes damage to its own tissues. Vandergheynst F, Gosset J, van de Borne P, Decaux G. Myopericarditis revealing adult-onset Still's disease. google_color_bg = "FFFFFF"; google_color_border = "FFFFFF"; Devika Gupta1, Rajat Jagani1, Satish Mendonca2, Khushi Ram Rathi1 Here, we report an unusual manifestation of AOSD in a 40-year-old male who presented to our hospital with pyrexia of unknown origin and rash of 3 weeks duration. Chronic myocardial ischemia due to diffuse coronary atherosclerosis can cause cardiomyopathy of the dilated type (DCM). The body responds as if normal tissues are infected or somehow abnormal. Background. Objective: To increase awareness of giant cell myocarditis (GCM), its pathogenesis, and treatment.