In conclusion, our patient report and recent literature reports suggest that USG during performance of nerve blocks does not completely eliminate the risk of accidental intravascular or intraneural9,10injection, and underscores the importance of strict adherence to all safety recommendations regarding the injection of LA during ultrasound-guided regional blocks. Reasons for misuse of prescription medication among physicians undergoing monitoring by a physician health program. Scopus is Elsevier's abstract and citation database launched in 2004. 2012; 126: 697-706. He developed swelling, pallor, and pain in the thumb. Avoid IV extravasation and accidental injection (e.g., from an auto-injector device). So, an EPINEPH rine autoinjector is appealing as a properly labeled unit dose that can be employed within seconds to treat the emergency, and the contents cannot be administered IV. Drug administration errors appear to be a major source of iatrogenic harm to hospitalized patients. Monitor the patient as soon as possible (pulse, blood pressure, ECG, pulse oximetry) in order to assess the response to adrenaline. Clinical Research in Cardiology. An alternative explanation is that the associated intravascular administration of epinephrine, which expectedly caused a hypertensive response, disrupted the blood–brain barrier and the defective blood–brain barrier produced sufficient cerebral edema to generate the witnessed symptoms. [3] Härle T, Kronberg K, Nef H, Möllmann H, Elsässer A. Inverted Takot-subo cardiomyopathy following accidental intravenous administration of epinephrine in a young woman. Epinephrine, also known as adrenaline, is a medication and hormone. IndexCopernicus Accidental migration of an epidural catheter into a blood vessel is often detected by hemodynamic changes after injecting an epidural test dose containing epinephrine. 2013; 27: 1451-1452. Treatment included topical … Copyright © 2014 The Authors. A case has even been reported with submucosal injection of very low concentrations of 1:100.000 in patients with variant In most cases, the outcome is favorable. It is also used to treat anaphylaxis caused by unknown 3 The patient’s symptoms of agitation and loss of consciousness were likely from hypertensive … provide readers a transparent and publisher-neutral data & statistics information about the journal. Western Journal of Emergency Medicine. 3 Drug administration errors appear to be a major source of iatrogenic harm to hospitalized patients. Journal of Korean Medical Science. Association of working hours and patient safety competencies with adverse nurse outcomes: a cross-sectional study. Adrenaline Bitartrate 4. Epinephrine is a key drug used in resuscitation, including advanced life support situations. Department of Emergency Medicine, Nowon Eulji Medical Center, Eulji University, Seoul. Adrenaline (epinephrine) IV infusion Newborn use only 2020 ANMF consensus group Adrenaline (epinephrine) IV infusion Page 1 of 3 Alert 1:10,000 (1 mg/10 mL) ampoule is the preferred preparation for adrenaline infusion. provide readers a transparent and publisher-neutral data & statistics information about the journal. We report a case of a 12-year-old boy presenting with Journal Citation Reports/Science Edition Prescription drug monitoring programs: examining limitations and future approaches. Scopus covers nearly 36,377 titles (22,794 active titles and 13,583 Inactive titles) from approximately 11,678 publishers, of which 34,346 are peer-reviewed journals in top-level subject fields: life sciences, social sciences, physical sciences and health sciences. Upon further evaluation, echocardiography revealed left ventricular wall motion abnormality with reduced ejection fraction. This debate regarding IV vs. IM epinephrine in anaphylaxis has actually been raging since the turn of the century. [1] Spina R, Song N, Kathir K, Muller DWM, Baron D. Takotsubo cardiomyopathy following unintentionally large subcutaneous adrenaline injection: a case report. Accidental self-injection of intravenous epinephrine by healthcare personnel. Epinephrine Injection, USP is a sterile, nonpyrogenic solution administered parenterally by the intravenous or intracardiac (left ventricular chamber) routes, or via endotracheal tube into the bronchial tree.Each milliliter (mL) contains epinephrine 0.1 mg; sodium chloride 8.16 mg; sodium metabisulfite added 0.46 mg; citric acid, anhydrous 2 mg and sodium citrate, dihydrate 0.6 mg added as buffers. [15] Son YJ, Lee EK, Ko Y. The overall objectives of the Foundation are to promote and develop health education and research programs. Journal Citation Reports/Science Edition aims to evaluate a journal’s value from multiple perspectives including the journal impact factor, descriptive data about a journal’s open access content as well as contributing authors, and This blog will doubtless elicit several comments discussing European Heart Journal Case Reports. Accidental Epinephrine Injections Epinephrine auto-injectors are widely used to treat severe allergic reac-tions or anaphylaxis. Poster Session, August 30, 2012. accidental IV epinephrine that have caused coronary vasospasm (1), angina (2) or even acute MI (Ref). International Journal of Environmental Research and Public Health. The proce-dure was terminated and the colonoscope was retrieved. More than 53 million records and 1.18 billion cited references date back from 1900 to present. In 2004, the Institute for Safe Medication Practices reported the death of a The following incident is a medication error case report which illustrates one way that incorrect medication may be administered. They often, particularly in the case of epinephrine, have catastrophic consequences both for the patient and the well-meaning provider. Scopus Epinephrine Hydrochloride 9. Adrenaline Acid Tartrate 3. The error was due to problem with medicine storage, misplaced medication, misreading a medication label and wrong selection. After a short stay in the intensive care unit as the vital signs were affected, the patient was transferred to the ward on the second day of hospitalization and was well enough to be discharged on the fifth day. 2020; 2: yty043. Accidental Injections of Epinephrine (EpiPen) Print Self-administrated shots of epinephrine (often referred to by the brand name EpiPen or epinephrine pen) are life-saving devices which can halt an allergic reaction and give a patient time to get to a hospital. Adrenaline (epinephrine) IV infusion 2016 NMF Consensus Group Adrenaline (epinephrine) IV Infusion Page 1 of 4 This is a printed copy refer to the electronic system for most up to date version Alert 1:10,000 (1 mg/10 mL) ampoule is the preferred preparation for adrenaline infusion. [12] Griggs C, Weiner S, Feldman J. 2020; 33: 28-30. 2016; 52: 91-93. Symjepi 2021.doi:10.22514/sv.2021.033. IV epinephrine was accidentally administered instead of midazolam at colonoscopy. 2017; 229: 67- 70. Alexandria Journal of Medicine. [6] Taneli Väyrynen MJ, Luurila HO, Määttä TK, Kuisma MJ. 2015; 16: 67-70. Adrenaline Tartrate 6. Epinephrine Epinephrine 2014-12-13 00:00:00 Reactions 1531, p84 - 13 Dec 2014 Takotsubo cardiomyopathy: case report A 37-year-old woman developed takotsubo cardiomyopathy following accidental IV administration of epinephrine [adrenaline] for allergic reaction. Created as SCI in 1964, Science Citation Index Expanded now indexes over 9,200 of the world’s most impactful journals across 178 scientific disciplines. Journal of Emergency Medicine. Accidental intravenous administration of racemic adrenaline: two cases associated with adverse cardiac effects. [2] Brian HR, Brian G. Allergy and anaphylaxis. [7] Surineni K, Afzal MR, Barua R, Parashara D. Epinephrine-induced Takotsubo cardiomyopathy. Epinephrine is a strong vasoconstrictor. The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications. Epinephrine is in a class of medications called alpha- and beta-adrenergic agonists (sympathomimetic agents). They often, particularly in the case of epinephrin… Adrenaline Hydrochloride 5. Chemical Abstracts Service Source Index The error resulted in intervention (hospital admission and monitoring) but did not result in harm or death. They often, particularly in the case of epinephrine, have catastrophic consequences both for the patient and the well-meaning provider. IV epinephrine was accidentally administered instead of midazolam at colonoscopy. For now, there are more than 58,000 scientific journals registered at ICI. Lidocaine Hydrochloride and Epinephrine Injection contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and Inappropriate drug use, accidental or otherwise, can pose a great risk. Epinephrine was accidentally administered intravenously instead of midazolam at colonoscopy. Tintinalli’s emergency medicine: a comprehensive study guide (pp. [5] André MC, Hammer J. Life-threatening accidental intravenous epinephrine overdose in a 12-year-old boy. We report two cases of accidental injection of epinephrine into the digits that were successfully treated with subcutaneous phentolamine injection with no adverse events. 9th edn. A physician in a Family Practice training program accidentally injected epinephrine into his left thumb while reading the operating instructions of an autoinjector (Epipen ®). regard to intrathecal injection, either intentional or accidental. [5] Inhaled epinephrine may be used to improve the symptoms of croup. European Journal of Emergency Medicine. The CAS Source Index (CASSI) Search Tool is an online resource that can quickly identify or confirm journal titles and abbreviations for publications indexed by CAS since 1907, including serial and non-serial scientific and technical publications. Federal Practitioner. The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The IV route for injection of epinephrine must be used with extreme caution and is best reserved for specialists familiar with IV use of epinephrine (adrenaline). Other disastrous outcomes have occurred in the setting of inadvertent overdose of IV epinephrine including cardiogenic shock, ventricular tachycardia, and severe myocardial ischemia 1. Reverse Takotsubo cardiomyopathy in the setting of anaphylaxis treated with high-dose intravenous epinephrine. Accidental hypothermia is a life threatening condition that can lead to a challenging resuscitation. The device is a single-use system containing a spring-loaded needle which will release 0.15mg or 0 A 45-year-old man suffered cardiopulmonary arrest in the field, and was treated by ACLS, including the administration of a number of medications through a … Journal of Anesthesia, Intensive Care, Emergency and Pain Medicine, Accidental self-injection of intravenous epinephrine by healthcare personnel, 1Department of Emergency Medicine, Nowon Eulji Medical Center, Eulji University, Seoul, Republic of Korea, *Corresponding Author(s): Heebum Yang E-mail: heebeom@gmail.com. While epinephrine is a life-saving drug for many, accidental administration errors pose a risk of lethal heart arrhythmias and have resulted in patient deaths. 1991; 63: 581-591. Pediatric Emergency Care. The Geneva Foundation for Medical Education and Research (GFMER) is a non-profit organization established in 2002 and it works in close collaboration with the World Health Organization (WHO). The very young, old, and intoxicated patient are at high risk to developing hypothermia, even in temperate climates. Epinephrine injection is used along with emergency medical treatment to treat life-threatening allergic reactions caused by insect bites or stings, foods, medications, latex, and other causes. We use cookies to help provide and enhance our service and tailor content and ads. The treatment of SCMP induced by epinephrine is largely conservative with a symptomatic approach. discovered. The overall objectives of the Foundation are to promote and develop health education and research programs. Still, we agree with NCCN that the presence of a vial or ampul of EPINEPHrine in the wrong hands invites accidental IV injection when the patient has an IV line established. The manuscript was previously presented as a poster in the 14th International Congress of the Egyptian Society of Hepatology, Gastroenterology and Infectious Diseases in Alexandria. 1. Embase This is a single case report of the accidental intra-arterial injection of epinephrine during a cardiac resuscitation. [4] Khoueiry G, Abi Rafeh N, Azab B, Markman E, Waked A, AbouRjaili G, et al. Epinephrine Bitartrate 7. Copyright © 2021 Elsevier B.V. or its licensors or contributors.