thrombocytopenia ppt for nursing students
Immune thrombocytopenia can occur in conjunction with a number of other disorders. See our User Agreement and Privacy Policy. See our Privacy Policy and User Agreement for details. An approach to a patient with Thrombocytopenia, Safety and infection control - Archer NCLEX webinars, No public clipboards found for this slide. Platelets stop bleeding by clumping and forming plugs in blood vessel injuries.Thrombocytopenia often occurs as a result of a separate disorder, such as leukemia or an immune system problem. 5. The answer: She's using NURSING.com videos to supplement the classroom with clear, concise, and to-the-point lectures taught by practicing nurses. Newer strategies for the treatment of heparin- induced thrombocytopenia. The uncleaved multimers induce the adhesion and aggregation of platelets in flowing blood. Within a few hours after receiving the woman's blood, Harrington's platelet count dropped. Some patients may have delayed onset HIT which can start as late as 9 days after exposure to heparin and may occur until 40 days after exposure. In Panel A, in normal subjects, ADAMTS 13 (von Willebrand factor-cleaving metalloprotease) molecules attach to binding sites on endothelial-cell surfaces and cleave unusually large multimers of von Willebrand factor as they are secreted by stimulated endothelial cells. Multiple platelet transfusions can cause platelet refractoriness ( alloimmunization) and also, other transfusion related complications. World's Best PowerPoint Templates - CrystalGraphics offers more PowerPoint templates than anyone else in the world, with over 4 million to choose from. Or it can be a side effect of taking certain medications. Schematic representation of the origin and development of megakaryocytes : - The pluripotential stem cell produces a progenitor cell committed to megakaryocyte differentiation (Meg-CFC) which undergoes mitosis. Upon completion of endomitosis, the immature progenitor cells become large, morphologically identifiable mature megakaryocytes MEGAKARYOCYTE now sheds the platelets. One good example is HIT. Various nursing intervention for thrombocytopenia disease is mentioned in the following: Assess the Patient for any signs symptoms of unusual bleeding, such as as- Epistaxis, Hemoptysis, ⦠The condition can be inherited or acquired. If you continue browsing the site, you agree to the use of cookies on this website. You can change your ad preferences anytime. If argatroban infusion rate is >2mcg/kg/min reduce dose to <2mcg/kg/min first and then, measure inr after 4 hours – now, if INR > 4, can stop argatroban, Why less than 100k : A prospective cohort of healthy subjects with platelet counts between 100 and 150 x 10 9 /L had a 10-yr probability of developing persistent platelets counts < 100 x 10 9 /L of only 6.9% . Rx HCV-TP discussed earlier. Further evidence suggesting that splenomegaly and portal hypertension are not the only factors to explain thrombocytopenia in chronic liver disease is the finding that thrombocytopenia has been shown to endure after surgical portal decompression with transjugular intrahepatic portosystemic shunt (TIPS) in cirrhotic patients. After 4 weeks, patients were evaluated before initiation of the antiviral treatment phase of the trial. The Meg-CFC eventually stops mitosis and enters endomitosis during which neither cytoplasm nor nucleus divides but DNA replication proceeds and gives rise to polyploid immature precursor cells. HIT can occur up until 30 days even after stopping heparin due to circulating antibodies. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. Thrombocytopenia in pregnancy is a common reason for hematology consultation. you have to do a nursing careplan on thrombocytopenia. The most common causes and differential diagnosis of In-patient and Outpatient presentations of Thrombocytopenia is discussed here. When urgent increase needed always IVIG vs. Anti D, 1. Proposed Relation among the Absence of ADAMTS 13 Activity in Vivo, Excessive Adhesion and Aggregation of Platelets, and Thrombotic Thrombocytopenic Purpura.