endobj /Rect [460.799999 45.9800000 537.599999 61.3400000] Resident bacteria play an important role in initiating and perpetuating gastrointestinal inflammation. Bacteria may also overgrow due to a lack of clearance of the small intestine, or changes in structure. /Border [0 0 0]

/Type /Action << << The other 47 infants didn't seroconvert or develop T1D (control). /S /URI << /A Undernutrition (UN) is a worldwide concern affecting morbidity and mortality among children, but the safety and long-term efficacy of its current treatments remain controversial. They are among the leading pathogens isolated in the setting of intra-abdominal infections. /Subtype /Link 12 0 obj endobj /SMask /None endobj Bacteroides dorei is a species of bacteria within the genus Bacteroides, first isolated in 2006.It is found in the intestinal systems of humans and animals. << )���� A|���F)�">�*�G$�B�CDqՠ����.��p��躚(AD���韜�=-�40�߮OY��s��y~���Ӷ�!�B!�B!�B!�B!�B!�B!�B!�B!�B!�B!�B!�B!��K��6|~s>4�G�IA!���k�����K���:+ϐ9ɫ#F/�Y�g��´�n�*�����Д�ֹa�،ζW��@�5$~�h�v�vIo;�=�ǹJK�{p:l5?�&�/{*p���;!�M�1��~���|j|�'2!�B(Z��`AcF.,+=�V��~E!������O��ޛ�l�+B!��-�WA!�Ç�VW�z�T���W�B�Zȯ,�+��B!~B�U��I�ʕ�~E!�?�r� /A >> /URI (https://doi.org/10.1172/JCI109859) The secreted protease was similar in action to the protease within the organism, in that it had a broad pH optimum of 6-9, a Km app. /S /URI /URI (http://www.jci.org/tags/51?utm_campaign=cover-page&utm_medium=pdf&utm_source=content) Research is being conducted to better understand the relationship Bacteroides dorei has on the human intestinal system and the autoimmune disease, Type 1 … >> /Border [0 0 0]

/Subtype /Link ~�9ɫM䪾�n��c8,Њү!��_x�W�Jіr�vew\�����S��Vs�W�B�/='�,ˀ���ʳ����+B!���U������~ �b�D��l�+B!������!�����͛5�"-�!��B!���~u��~S��'�L�0��+B!������g^K_��~E!��k����.i� Table 1. /A Methods. endobj 8 0 obj

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>> /URI (http://www.jci.org) /S /URI This man- ... Bacteroides vulgatus, Enterococcus faeca lis, E. coli–enteroinvasive, Klebsiella “Ugly” bacteria /SM 0.02 >> We performed a meta-analysis of the available data to provide a more precise estimate of the association between Bacteroides level in the gut and IBD. /Height 94 >> >> Multiple studies have reported associations between inflammatory bowel disease (IBD) and the flora disequilibrium of Bacteroides .

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The Bacteroides fragilis group consists of species of obligate anaerobic bacteria that inhabit the human gut. /Width 800 /Rect [42.2399999 534.799999 142.079999 550.159999]

/S /URI Metagenomic sequencing results showed significantly higher composition of

/Type /XObject � y6nǶC^���F�"�B�_`�_!���^h�ۍ~E!�� ($vRtV�#�)�y�������&^����K�ּ[2'y5Я#j�������+B!��0%��@ �*(8f��3���n��ı�c#ҽ_Y�~E!���� 14 0 obj The following species were identified in the jejunal fluid samples obtained from the patients: Escherichia coli, Candida albicans, Pseudomonas aeruginosa, enterococcus, Lactobacillus bifidus, Bacteroides vulgatus, Bacteroides thetaiotaomicron, Bacteroides uniformis, Eubacterium lentum, …

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We previously demonstrated that six commensal bacteria including Bacteroides vulgatus caused more aggressive colitis and gastritis in HLA-B27 transgenic rats than did the other five bacteria without B. vulgatus . 7 0 obj /S /URI

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Out of the 76 infants, 29 seroconverted to T1D autoimmune related cases, of which of 22 later on developed T1D (cases). /A << /ColorSpace /DeviceRGB Oral bacteria such as Fusobacterium nucleatum or Peptostreptococcus may also play a role in the overgrowth. /Type /Annot In this case, you might see high numbers of E. coli, Klebsiella, Proteus, Bacteroides or Clostridium 3.

<< Previous research has shown that individuals who are genetically predisposition to various autoimmune diseases have significant differences in bacteria composition than non-genetically predisposition individuals. >> endobj endobj /A /Type /Annot '���W�B�7�W�B!�B�"�B��!�B��Я!�B��~E!�b-�+B!�k�_B!�X��B!�Z�W�B!�B�"�B��!�B��Я!�B��~E!�b-�+B!�k�_B!�X��B!�Z�W�B!�B�"�B��!�B��Я!�B��~E!�b-�+��5�W�ikV�*+=q��}"���=�T���As��'������c�mm��>�� K���][�Rt��ii��!��ț�;v�6����{*�\x�`���w���s�Kq�RX���A�(c��Q �lx�g�4T��Q��� /SA true This difference in bacteria composition in the gut system is increasingly believed to be highly important in understanding autoimmune diseases such as Type1 Diabetes. /Rect [45.1199999 58.4600000 171.840000 73.8200000]

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They took stool samples of 76 children looking at the early development of microbial communities from 4–6 months of age until 2.2 year old. /ca 1.0 Selected bacteroides species secreted various amounts of protease and glycosidase into their growth medium.

/Subtype /Link Treatment with antibacterial agents alters the normal flora of the colon leading to overgrowth of C. difficile.

/Subtype /Link

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